The DriverPacks were created as being an addition to the drivers already delivered on your Win disc and hence do not contain those that are already present (unless there's an updated version available).
For a lot of old HW, there probabaly won't be any newer drivers than thos already on the disc so removing them will drop support for these.
Bad idea.

Also, nLite may be capable of removing fundamental drivers (IDE, USB, LPT and whatnot), which are NOT covered by the DriverPacks!

The only reason I can think of you may want to delete these drivers anyway is to save space on the disc.
If you are really that desparate (there's a lot of other, unnecessary stuff you can delete with nLite), you'd have to check whether DriverPacks contain updated drivers of these you plan to remove by checking out the device listing for each pack.
Don't think it's worth the trouble, though...

I simply want to know, if it is secure to delete all windows drivers with nlite (not driver suppport, I mean the drivers section). Because I don't want any old drivers, Driverpacks offers already support for all drivers right????